Sebaceous hyperplasia in neonates and adults

Sebaceous hyperplasia in neonates and adults

Diffuse sebaceous-gland hyperplasia.

Diffuse sebaceous-gland hyperplasia is a rarevariant of sebaceous-gland hyperplasia that isdistinct from the well-known circumscribed type.The term presenile sebaceous hyperplasia has beenutilized to describe this entity that is distinguishedby specific features, which include confluence oflesions that results in the formation of large plaqueson the face, the sparing of periorificial regions, a...

Areolar sebaceous hyperplasia.

Sir, Sebaceous hyperplasia is a common disorder of the face in adults, particularly men. The lesions, which are usually found on the forehead, cheeks and nose, consist of yellowish papules with central umbilication representing a widely dilated infundibular ostium (1). In 1985, Catalano & Ioannides (2) reported the case of a 37-year-old woman who noticed the development of extensive yellow plaq...

Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma.

AIMS Regulation of cell cycle progression is a fundamental control process, linked to cellular differentiation and apoptosis in normal tissues. p21(WAF1) is a nuclear protein that regulates cell cycle progression. p21(WAF1) can be transcriptionally upregulated by p53, but may be activated independently of p53-for example, during terminal differentiation. Loss of topological control of p21(WAF1)...

Pigmented trichoblastoma with sebaceous hyperplasia.

Trichoblastoma is a rare benign trichogenic tumour with epithelial and mesenchymal components recapitulating the germinal hair bulb and associated mesenchyme. A 50- year- old male patient presented with slowly enlarging circumscribed solid nodule measuring 4x3x4.5 cm over the tip of the nose. Microscopy of tumour revealed nodular tumour spanning the entire dermis with collection of mesenchymal ...